Quick Review Cheat Sheets:
Choledochocysts: abdominal pain/mass/jaundice mostly in kids
|
Type |
Description |
RX |
|
Type 1 |
fusiform dilatation of the extrahepatic biliary duct |
complete resection with Roux-en-Y |
|
Type 2 |
Diverticulum of the extrahepatic biliary duct |
excision with primary choledochorrhapy |
|
Type 3 |
Dilatation of intraduodenal portion of CBD |
Transduodenal cyst excision |
|
Type 4 |
Multiple intrahepatic bile duct cysts |
selective management |
|
Type 5 |
single or multiple intrahepatic biliary cysts |
selective managment |
Chemotherapeutic Agents:
|
Agent |
Side Effect |
|
Doxorubicin |
bone marrow suppression, alopecia, cardiomyopathy |
|
Etoposide |
alopecia, hepatotoxicity, diarrhea, bone marrow suppression |
|
Streptozocin |
kidney toxicity, hyperglycemia |
|
Vincristine |
peripheral neuropathy, constipation, diarrhea |
|
Cisplatin |
renal toxicity |
|
Cyclophosphamide |
hemorrhagic cystitis |
|
Procarbazine |
hypertension |
|
l-Asparaginase |
acute pancreatitis |
|
Bleomysin |
pulmonary toxicity (pneumonitis or fibrosis), hyperpigmentation |
Collagen:
|
Type |
Description/location |
|
Type 1 |
high tensile strength, dermis 80%, scars, bone 90%, tendons |
|
Type 2 |
structural proteins, cartilage 50% (type IX as well), vitreous humor |
|
Type 3 |
embryonic tissue, vessels, keloids, granulation tissue |
|
Type 4 |
all basement membranes |
Wound Healing:
|
Phase |
Name |
Timing |
Predominate Cell |
Events |
|
1 |
Inflammation |
0-72hours (3 days) |
Platelets Neutrophils Macrophages |
hemostasis, epithelialization, angiogenesis |
|
2 |
Proliferation |
3 days - 3 weeks |
fibroblasts |
wound contraction by myofibroblasts occurs |
|
3 |
Maturation |
3 weeks - 2 years |
Type 3 collagen replaced by Type I collagen |
collagen deposition maximal at 21days, but wound only 15% tensile strength, at 6 weeks reaches 80-90% tensile strength |